Gabapentin + Nortriptyline treats neuropathic pain. Gabapentin reduces nerve cell activity by modulating calcium channels, while Nortriptyline, a tricyclic antidepressant, increases serotonin and noradrenaline levels to block pain signals in the brain. Common side effects include constipation, dry mouth, dizziness, sleepiness, weight gain, blurred vision, tiredness, orthostatic hypotension, increased heart rate, and uncoordinated body movements.
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